Article
Additional molecular bases of the clinically important p blood group phenotype.
Transfusion - 1 Jul 2003
Hellberg Asa, Steffensen Rudi, Yahalom Vered, Sojka Birgitta Nilsson, Heier Hans Erik, Levene Cyril, Poole Joyce, Olsson Martin L
Abstract excerpt
BACKGROUND: The purpose of this study was to explore the molecular basis of the p phenotype by analysis of the recently cloned 4-alpha-galactosyltransferase gene responsible for synthesis of Pk (Gb3) antigen. STUDY DESIGN AND METHODS: Forty samples from individuals of eight different nationalities were investigated by serologic methods and DNA sequencing of the Pk gene. RESULTS: Ten different Pk-null alleles, of...
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