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Article

Genetic damage induced by in vitro irradiation of human G0 lymphocytes with low-energy protons (28 keV/microm): HPRT mutations and chromosome aberrations.

Radiation research - 1 Jul 2003

Mognato Maddalena, Bortoletto Elisabetta, Ferraro Paola, Baggio Laura, Cherubini Roberto, Canova Sabrina, Russo Antonella, Celotti Lucia

Abstract excerpt

Cell survival, mutations and chromosomal effects were studied in primary human lymphocytes exposed in G0 phase to a proton beam with an incident energy of 0.88 MeV (incident LET of 28 keV/microm) in the dose range 0.125-2 Gy. The curves for survival and mutations at the hypoxanthine-guanine phosphoribosyl transferase locus were obtained by fitting the experimental data to linear and linear-quadratic equations,...

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Identifiers

PMID: 12816523
DOI: 10.1667/0033-7587(2003)160[0052:gdibiv]2.0.co;2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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