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Article

Interactions of sperm perinuclear theca with the oocyte: Implications for oocyte activation, anti‐polyspermy defense, and assisted reproduction

10 Jun 2003

Abstract excerpt

Perinuclear theca (PT) is the cytoskeletal coat of mammalian sperm nucleus that is removed from the sperm head at fertilization. PT harbors the sperm borne, oocyte-activating factor (SOAF), a yet-to-be-characterized substance responsible for triggering the signaling cascade of oocyte activation, thought to be dependent on intra-oocyte calcium release. The present article reviews the current knowledge on the...

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PMID: 12811742
DOI: 10.1002/jemt.10350

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