Article
Analysis of the TGF-beta1 promoter polymorphism (C-509T) in patients with chronic periodontitis.
Journal of clinical periodontology - 1 Jun 2003
de Souza A P, Trevilatto P C, Scarel-Caminaga R M, de Brito R B, Line S R P
Abstract excerpt
BACKGROUND: A polymorphism in the promoter region of the transforming growth factor beta-1 (TGF-beta1) gene was described at position -509. This polymorphism represents a C-to-T base exchange, which creates a YY1 consensus sequence in an area involved with down transcription regulation. This polymorphism has been associated with risk for asthma and allergies. In this study we investigated the association between...
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