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Article

Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.

Nutritional neuroscience - 1 Jun 2003

Joseph J A, Denisova N A, Arendash G, Gordon M, Diamond D, Shukitt-Hale B, Morgan D

Abstract excerpt

Previously, we showed that blueberry (BB) supplementation reversed the deleterious effects of aging on motor behavior and neuronal signaling in senescent rodents. We now report that BB-fed (from 4 months of age) APP + PS1 transgenic mice showed no deficits in Y-maze performance (at 12 months of age) with no alterations in amyloid beta burden. It appeared that the protective mechanisms are derived from BB-induced...

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PMID: 12793519
DOI: 10.1080/1028415031000111282

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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