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Article

A simple and rapid approach for human herpesvirus type 8 subtype characterization using single base extension.

Letters in applied microbiology - 1 Sept 2021

Hulaniuk M L, Corach D, Trinks J, Caputo M

Abstract excerpt

Sequence analysis of the ORFK1 of human herpesvirus type 8 (HHV-8) allows the identification of six major subtypes (A-F), which are related to human migrations and the clinical progression of Kaposi's sarcoma. Sequencing and subsequent phylogenetic analysis of ORFK1 is considered to be the most reliable method for HHV-8 genotyping. However, it exhibits challenges and limitations. Herein, we designed and validated...

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PMID: 34048079
DOI: 10.1111/lam.13515

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