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Article

Overestimation of genetic risks owing to small sample sizes in cardiovascular studies.

Clinical genetics - 1 Jul 2003

Morgan T M, Coffey C S, Krumholz H M

Abstract excerpt

We sought evidence of publication bias to explain conflicting findings in studies of angiotensin-converting enzyme deletion polymorphism (ACE D) and glycoprotein IIIa PlA2 (PLA2) polymorphism and the risk of myocardial infarction. Factor 5 Leiden (F5L), a well-established thrombotic risk factor, served as an internal comparison. We conducted systematic reviews of published studies involving ACE D, PLA2, F5L and...

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Source

Identifiers

PMID: 12791034
DOI: 10.1034/j.1399-0004.2003.00088.x

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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