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Article

Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias.

PLoS medicine - 1 Dec 2006

Serrano Norma C, Díaz Luis A, Páez Maria C, Mesa Clara M, Cifuentes Rodrigo, Monterrosa Alvaro, González Adriana, Smeeth Liam, Hingorani Aroon D, Casas Juan P

Abstract excerpt

BACKGROUND: Inappropriate activation of the renin-angiotensin system may play a part in the development of preeclampsia. An insertion/deletion polymorphism within the angiotensin-I converting enzyme gene (ACE-I/D) has shown to be reliably associated with differences in angiotensin-converting enzyme (ACE) activity. However, previous studies of the ACE-I/D variant and preeclampsia have been individually...

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Identifiers

PMID: 17194198
DOI: 10.1371/journal.pmed.0030520
PMCID: PMC1716194

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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