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Article

Pharmacology of Neural Tube Defects

1 Jun 2003

Abstract excerpt

The pharmacology of neural tube defects (NTDs) is a complex issue. Several theories regarding the etiology of NTDs emphasize the importance of interactions between genetic, environmental, and biochemical factors at a key point in time. One such factor is chronic drug therapy, a potential consequence of which is the formation of toxic drug metabolites, including free radicals (FRs), which have been implicated in...

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PMID: 12790883
DOI: 10.1046/j.1528-1157.44.s3.3.x

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