Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic variants in the MYOC/TIGR gene in patients with primary open-angle, exfoliative glaucoma and unaffected controls.

Ophthalmic genetics - 1 Jun 2003

Jansson Mattias, Marknell Towa, Tomic Lidija, Larsson Lill-Inger, Wadelius Claes

Abstract excerpt

One of the leading causes of blindness in the world is glaucoma. The most common form is primary open-angle glaucoma (POAG). The only gene identified so far as being associated with POAG is the MYOC gene; 2-4% of the patients have been reported to carry mutations in this gene. Exfoliative glaucoma is a secondary glaucoma, in which one of the symptoms is exfoliations on the lens capsule and anterior segment of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exfoliation Syndrome

Share to Eye Proteins

Share to Glaucoma, Open-Angle

Share to Glycoproteins

Share to Sweden

Share to Trabecular Meshwork

Source

Identifiers

PMID: 12789574
DOI: 10.1076/opge.24.2.103.13997

Genes

MYOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic variants in the MYOC/TIGR gene in patients with primary open-angle, exfoliative glaucoma and unaffected controls.PMID 12789574Read ↗

MYOC Gene Sequencing Analysis in Primary Open-Angle Glaucoma Patients from the Centre Region of Portugal.Semantic proximity Read ↗

Mutations in MYOC gene of Indian primary open angle glaucoma patients.Semantic proximity Read ↗

Founder TIGR/myocilin mutations for glaucoma in the Québec population.Semantic proximity Read ↗

Molecular and Clinical Evaluation of a Patient Hemizygous for TIGR/MYOCSemantic proximity Read ↗

Rapid mutation detection by the transgenomic wave analyser DHPLC identifies MYOC mutations in patients with ocular hypertension and/or open angle glaucoma.Semantic proximity Read ↗

Myocilin variants in Indian patients with open-angle glaucoma.Semantic proximity Read ↗

Myocilin mutations among primary open angle glaucoma patients of Kanyakumari district, South India.Semantic proximity Read ↗

Identification of a novel MYOC mutation, p.(Trp373), in a family with open angle glaucoma.Semantic proximity Read ↗

Correlation between genotype and phenotype in primary open angle glaucoma of Brazilian families with mutations in exon 3 of the TIGR/MYOC gene.Semantic proximity Read ↗

Variations in the myocilin gene in patients with open-angle glaucoma.Semantic proximity Read ↗

Polymorphisms in an intronic region of the myocilin gene associated with primary open-angle glaucoma--a possible role for alternate splicing.Semantic proximity Read ↗

Haplotype analysis of association of the MYOC gene with primary angle-closure glaucoma in a Han Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.