Article
Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1.
Rheumatology (Oxford, England) - 1 Oct 2003
Ye S, Pang H, Gu Y-Y, Hua J, Chen X-G, Bao C-D, Wang Y, Zhang W, Qian J, Tsao B P, Hahn B H, Chen S-L, Rao Z-H, Shen N
Abstract excerpt
OBJECTIVE: To identify disease-related genes and immune-regulatory pathways in the pathogenesis of systemic lupus erythematosus (SLE) by using gene expression profiling and protein-protein interaction analysis. METHODS: Peripheral white blood cell gene expression profiles of 10 SLE patients were determined by oligonucleotide microarray analysis. Clustering of the gene expression profile was compared with the...
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