Article
DNA-protein crosslinks and p53 protein expression in relation to occupational exposure to formaldehyde.
Occupational and environmental medicine - 1 Jun 2003
Shaham J, Bomstein Y, Gurvich R, Rashkovsky M, Kaufman Z
Abstract excerpt
BACKGROUND: Formaldehyde (FA) is classified as a probable human carcinogen. AIMS: To examine DNA protein crosslinks (DPC) and p53, which are generally known to be involved in carcinogenesis, in peripheral blood lymphocytes of workers exposed to FA. METHODS: DPC and p53 ("wild type" and mutant) were examined in peripheral blood lymphocytes of 186 workers exposed to FA (mean years of exposure = 16) and 213...
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