Article
Tissue engineering skeletal muscle for orthopaedic applications.
Clinical orthopaedics and related research - 1 Oct 2002
Payumo Francis C, Kim Hyun D, Sherling Michael A, Smith Lee P, Powell Courtney, Wang Xiao, Keeping Hugh S, Valentini Robert F, Vandenburgh Herman H
Abstract excerpt
With current technology, tissue-engineered skeletal muscle analogues (bioartificial muscles) generate too little active force to be clinically useful in orthopaedic applications. They have been engineered genetically with numerous transgenes (growth hormone, insulinlike growth factor-1, erythropoietin, vascular endothelial growth factor), and have been shown to deliver these therapeutic proteins either locally or...
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