Article
Functional expression of guinea pig growth hormone receptor and its mutants in mammalian cells.
Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica - 1 May 2003
Liao Zhi-Yong, Zhang Xin-Na, Jing Nai-He, Zhu Shang-Quan
Abstract excerpt
The cDNA of guinea pig (Cavia porcellus) growth hormone receptor (gpGHR) was cloned using RT-PCR in our laboratory. By sequence alignment, substitutions of amino acids conserved in other mammalian GHRs were found. For example, histidine-168 and tyrosine-332 equivalent to positions 170 and 333 in other mammalian GHRs, which were considered to be necessary for the dimerization of GHR and the specific GH-stimulated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
