Article
SAA1 gene polymorphisms and the risk of AA amyloidosis in Japanese patients with rheumatoid arthritis.
Modern rheumatology - 1 Jan 2006
Ajiro Junya, Narita Ichiei, Sato Fuminori, Saga Daisuke, Hasegawa Hisashi, Kuroda Takeshi, Nakano Masaaki, Gejyo Fumitake
Abstract excerpt
To investigate the precise modality of association between SAA1 gene polymorphisms and the development of AA amyloidosis in patients with rheumatoid arthritis (RA), Japanese patients with RA (n=153), among whom 29 were histologically diagnosed as having amyloidosis, were genotyped for three single nucleotide polymorphisms (SNPs), C-13T, C2995T, and C3010T, in the SAA gene. Pairwise linkage disequilibrium...
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