Article
[Preliminary study on NS5 region gene sequencing and variants of hepatitis G virus in China].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Mar 1999
Li B, Dong Z, Cheng Y
Abstract excerpt
OBJECTIVE: To study the genomic specificity and variation of Hepatitis G virus(HGV) in China. METHODS: The 141nt cDNA fragments locating at nonstructural region 5 (NS5) of HGV were obtained from the sera of 16 HGV infected patients by RT-nested-PCR using NS5 primers, then purified and directly sequenced by dideoxynucleotide chain termination method. RESULTS: The sequence diversity near the N-terminus of the...
Topics
- Adult
- Female
- Flaviviridae Infections
- GB virus C
- Genes, Viral
- Hepatitis, Viral, Human
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Sequence Analysis
- Viral Nonstructural Proteins
