Article
Immunoglobulin G Subisotype Responses of Pneumonic and Healthy, Exposed Foals and Adult Horses toRhodococcus equiVirulence-Associated Proteins
1 May 2003
Abstract excerpt
Rhodococcus equi causes severe pyogranulomatous pneumonia in foals and in immunocompromised humans. Replication of virulent isolates within macrophages correlates with the presence of a large plasmid which encodes a family of seven virulence-associated proteins (VapA and VapC to VapH), whose functions are unknown. Although cell-mediated immunity is thought to be crucial in eliminating R. equi infection, antibody...
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