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Article

Distal site aspartate is essential in the catalase activity of catalase-peroxidases.

Biochemistry - 13 May 2003

Jakopitsch Christa, Auer Markus, Regelsberger Günther, Jantschko Walter, Furtmüller Paul Georg, Rüker Florian, Obinger Christian

Abstract excerpt

Structural and biochemical characterization of aspartate 152 at the distal heme side of catalase-peroxidase (KatG) from Synechocystis PCC 6803 reveals an important functional role for this residue. In the wild-type protein, the side chain carboxyl group of Asp152 is 7.8 A apart from the heme iron and is hydrogen-bonded to two water molecules and a KatG-specific large loop. We have prepared the site-specific...

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PMID: 12731870
DOI: 10.1021/bi026944d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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