Article
Evolution of genotypic resistance to nucleoside analogues in patients receiving protease inhibitor-containing regimens.
Antiviral therapy - 1 Jan 1999
Pèrez-Olmeda M, Rubio A, Puig T, Gômez-Cano M, Ruiz L, Leal M, Clotet B, Soriano V
Abstract excerpt
The prevalence of genotypic resistance to nucleoside analogues (NA) was examined using a line probe assay (LiPA, Innogenetics, Spain) and a point mutation assay to test for codon 151 polymorphism in plasma from 34 individuals who had been exposed to NA for longer than 1 year. The testing was repeated in the same population after 6 months of being on a new potent protease inhibitor (PI)-containing antiretroviral...
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