Article
Incorporating cytochrome P450 3A4 genotype expression and FT-IR/Raman spectroscopy data as means of identification of breast tumors.
Biomedical sciences instrumentation - 1 Jan 2003
Miller Spencer O, Ewing Gideon P, Howard Carol, Tachikawa Hiroyasu, Bigler Steven A, Barber W Henry, Angel Michael, McDaniel D Olga
Abstract excerpt
We have evaluated the use of cytochrome P450 (CYP), 3A4 genotype and Fourier transform-infrared (RT-IR)/Raman spectroscopy as diagnostic tools for detection of breast tumors. CYP is involved in catalytic activity of oxidative metabolism of many chemicals in fatty tissues, and it plays a major role in biotransformation and detoxication of environmental contaminants. FT-IR and Raman spectroscopy have been used to...
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