von Hippel-Lindau disease: recent advances and therapeutic perspectives.

doi:10.1586/14737140.3.2.215

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Article

von Hippel-Lindau disease: recent advances and therapeutic perspectives.

Expert review of anticancer therapy - 1 Apr 2003

Richard Stéphane

Abstract excerpt

von Hippel-Lindau disease is a hereditary cancer syndrome predisposing carriers to the development of a panel of highly vascularized tumors such as central nervous system and retinal hemangioblastomas, endolymphatic sac tumors, clear-cell renal cell carcinomas, pheochromocytomas and pancreatic neuroendocrine tumors. The disease is the foremost cause of inherited renal cell carcinomas, which is induced by germline...

Topics

Genetic Predisposition to Disease
Humans
Mutation
von Hippel-Lindau Disease

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Open in PubMed

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PMID: 12722881
DOI: 10.1586/14737140.3.2.215

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