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Article

[EGF-induced signal transduction in clonal cells of epidermoid carcinoma A431].

Tsitologiia - 1 Jan 2003

Grudinkin P S, Bagaeva V V, Nikol'skiĭ N N

Abstract excerpt

A431 epidermoid carcinoma cells have an increased expression of EGF receptor. In contrast to many other cell lines and primary cells, these respond to EGF in high (more than 1 ng/ml) concentrations by cell cycle arrest, apoptosis and detachment. Clonal variants of A431 (1a and 8a), able to grow in the presence of EGF in high concentration, were previously developed in our laboratory (Gudkova, Sorokin, 1989). Here...

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Source

Identifiers

PMID: 12722480

Genes

EGF
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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