Article
Estimation of infection and recovery rates for highly polymorphic parasites when detectability is imperfect, using hidden Markov models.
Statistics in medicine - 30 May 2003
Smith Tom, Vounatsou Penelope
Abstract excerpt
A Bayesian hierarchical model is proposed for estimating parasitic infection dynamics for highly polymorphic parasites when detectability of the parasite using standard tests is imperfect. The parasite dynamics are modelled as a non-homogeneous hidden two-state Markov process, where the observed process is the detection or failure to detect a parasitic genotype. This is assumed to be conditionally independent...
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