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Article

The dynamics of natural Plasmodium falciparum infections.

PloS one - 1 Jan 2012

Felger Ingrid, Maire Martin, Bretscher Michael T, Falk Nicole, Tiaden André, Sama Wilson, Beck Hans-Peter, Owusu-Agyei Seth, Smith Thomas A

Abstract excerpt

BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on parasite dynamics are poorly understood. Acquisition and clearance rates of untreated infections are key elements of the dynamics of malaria, but estimating these parameters is challenging because of frequent super-infection and imperfect detectability of parasites. Consequently, information on effects of host immune...

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Identifiers

PMID: 23029082
DOI: 10.1371/journal.pone.0045542
PMCID: PMC3445515

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