Fibrinogen Kyoto II, a new congenitally abnormal molecule, characterized by the replacement of A alpha proline-18 by leucine.

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Article

Fibrinogen Kyoto II, a new congenitally abnormal molecule, characterized by the replacement of A alpha proline-18 by leucine.

Blood - 1 Jul 1991

Yoshida N, Okuma M, Hirata H, Matsuda M, Yamazumi K, Asakura S

Abstract excerpt

A new case of heterozygous dysfibrinogenemia characterized by an amino acid replacement in the NH2-terminal region of the fibrin alpha-chain was found in a 27-year-old woman with a bleeding problem. Her one-stage prothrombin time and activated partial thromboplastin time were slightly prolonged,...

Topics

Adult
Amino Acid Sequence
Chromatography, High Pressure Liquid
Congenital Abnormalities
Electrophoresis, Polyacrylamide Gel
Female
Fibrinogens, Abnormal
Genetic Variation
Humans
Leucine
Molecular Sequence Data
Proline

Source

Open in PubMed

Identifiers

PMID: 2070049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2070049-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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