Article
Association of partial epilepsy with brain-derived neurotrophic factor (BDNF) gene polymorphisms.
Epilepsy research - 1 Mar 2003
Kanemoto Kousuke, Kawasaki Jun, Tarao Yoko, Kumaki Tetsuo, Oshima Tomohiro, Kaji Ryuji, Nishimura Masataka
Abstract excerpt
In search of a gene polymorphism that may contribute to the development of partial epilepsy, we focused on brain-derived neurotrophic factor (BDNF), since the functional effects of insult-induced neurotrophin changes are reported to be protection against neuronal damage and stimulation of synaptic reorganization. Two hundred nineteen patients with partial epilepsy were selected for study and 311 individuals were...
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