Article
Functional analysis of a PcsB-deficient mutant of group B streptococcus.
FEMS microbiology letters - 11 Apr 2003
Reinscheid Dieter J, Ehlert Kerstin, Chhatwal Gursharan S, Eikmanns Bernhard J
Abstract excerpt
Group B streptococcus (GBS) is the major cause of bacterial sepsis and meningitis in neonates and poses a significant threat to parturient women. Recently, we identified in GBS the polypeptide PcsB, which is a protein required for cell separation of GBS, and which is also involved in the antibiotic sensitivity of these bacteria. In the present study, the introduction of the pcsB-carrying plasmid pATpcsB into the...
Topics
- Amino Acid Sequence
- Amino Acids
- Anti-Bacterial Agents
- Bacterial Proteins
- Cell Cycle Proteins
- Cell Wall
- Genetic Complementation Test
- Lactams
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation