Article
Differences in troglitazone action on glucose metabolism in freshly isolated vs long-term incubated rat skeletal muscle.
British journal of pharmacology - 1 Mar 2003
Gras Florian, Brunmair Barbara, Roden Michael, Waldhäusl Werner, Fürnsinn Clemens
Abstract excerpt
1. Exposure of isolated skeletal muscle to troglitazone has resulted in inconsistent findings ranging from inhibition to stimulation of fuel oxidation and the glycogenic pathway. To better understand such variation in outcome, the present study used isolated rat soleus muscle strips to examine the interdependent influences of prolonged maintenance in vitro and of troglitazone exposure. 2. If freshly isolated...
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