Article
Polygenic inheritance of otosclerosis.
The Annals of otology, rhinology, and laryngology - 1 Jan 2000
Mendlowitz J C, Hirschhorn K
Abstract excerpt
A large family has been studied and its pedigree traced for six generations. Fifteen relatives are known to have had otosclerosis. Of these, the only six individuals who developed this disease before the age of twenty were offspring of second-cousin marriages. Other children in the extended famil...
Topics
- Adult
- Epidemiologic Methods
- Female
- Genotype
- Humans
- Male
- Otosclerosis
- Pedigree
- Risk