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Article

Information theory-based analysis of CYP2C19, CYP2D6 and CYP3A5 splicing mutations.

Pharmacogenetics - 1 Apr 2003

Rogan Peter K, Svojanovsky Stan, Leeder J Steven

Abstract excerpt

Several mutations are known or suspected to affect mRNA splicing of CYP2C19, CYP2D6 and CYP3A5 genes; however, little experimental evidence exists to support these conclusions. The present study applies mathematical models that measure changes in information content of splice sites in these genes...

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Identifiers

PMID: 12668917
DOI: 10.1097/00008571-200304000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12668917-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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