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Article

Role of Mobile DNA in the Evolution of Vancomycin-Resistant <i>Enterococcus faecalis</i>

27 Mar 2003

Abstract excerpt

The complete genome sequence of Enterococcus faecalis V583, a vancomycin-resistant clinical isolate, revealed that more than a quarter of the genome consists of probable mobile or foreign DNA. One of the predicted mobile elements is a previously unknown vanB vancomycin-resistance conjugative transposon. Three plasmids were identified, including two pheromone-sensing conjugative plasmids, one encoding a previously...

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PMID: 12663927
DOI: 10.1126/science.1080613

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