Article
Clinical and experimental advances in congenital and paediatric cataracts.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Apr 2011
Churchill Amanda, Graw Jochen
Abstract excerpt
Cataracts (opacities of the lens) are frequent in the elderly, but rare in paediatric practice. Congenital cataracts (in industrialized countries) are mainly caused by mutations affecting lens development. Much of our knowledge about the underlying mechanisms of cataractogenesis has come from the genetic analysis of affected families: there are contributions from genes coding for transcription factors (such as...
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