Article
Association analysis of exonic variants of the GABA(B)-receptor gene and alpha electroencephalogram voltage in normal subjects and alcohol-dependent patients.
Behavior genetics - 1 Jan 2003
Winterer Georg, Mahlberg Richard, Smolka Michael N, Samochowiec Jerzy, Ziller Mario, Rommelspacher Hans-Peter, Herrmann Werner M, Schmidt Lutz G, Sander Thomas
Abstract excerpt
Based on pharmacologic evidence, it has been suggested that GABA(B) receptors may play a crucial role in the generation of alpha-electroencephalogram (EEG) oscillations. We tested whether three exonic variants of the gene encoding the human GABA(B) receptor (GABA(B)R1) modify scalp-recorded alpha-EEG voltage. One hundred twenty-eight patients suffering from alcoholism and 114 normal subjects were investigated....
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