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Article

Replicate real‐time PCR testing of DNA in maternal plasma increases the sensitivity of non‐invasive fetal sex determination

3 Feb 2003

Abstract excerpt

BACKGROUND: We determined fetal sex in pregnancies referred for invasive prenatal diagnosis procedures by analysis of DNA in maternal plasma. METHODS: Twelve pregnancies at risk of X-linked haemophilia and 32 pregnancies at risk of chromosomal aneuploidies at a gestational age ranging from 10 to 18 weeks recruited before chorionic villus sampling or amniocentesis were involved in the study. Male fetal DNA in...

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PMID: 12627426
DOI: 10.1002/pd.556

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