Article
Genetics and the pathophysiology of obesity.
Pediatric research - 1 May 2003
Clément Karine, Ferré Pascal
Abstract excerpt
Obesity is a complex disease that involves interactions between environmental and genetic factors. Obesity results from an imbalance between food intake and energy expenditure over several years. The genetic approach both in animal models and in humans has allowed immense progress in the understanding of body weight regulation. Monogenic forms of obesity in humans have been characterized and result from mutations...
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