Article
cDNA microarray analysis of individual Duchenne muscular dystrophy patients.
Human molecular genetics - 15 Mar 2003
Noguchi Satoru, Tsukahara Toshifumi, Fujita Masako, Kurokawa Rumi, Tachikawa Masaji, Toda Tatsushi, Tsujimoto Atsumi, Arahata Kiichi, Nishino Ichizo
Abstract excerpt
We have developed a novel cDNA microarray encompassing 3500 genes expressed in skeletal muscle. With this system, we have performed the first study of gene expression in samples from individual patients. We analyzed muscle specimen from individuals with Duchenne muscular dystrophy to identify differences among patients. Among the variably expressed genes, we focused on the expression of the genes encoding...
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