Article
Large-scale identification of single-feature polymorphisms in complex genomes.
Genome research - 1 Mar 2003
Borevitz Justin O, Liang David, Plouffe David, Chang Hur-Song, Zhu Tong, Weigel Detlef, Berry Charles C, Winzeler Elizabeth, Chory Joanne
Abstract excerpt
We have developed a high-throughput genotyping platform by hybridizing genomic DNA from Arabidopsis thaliana accessions to an RNA expression GeneChip (AtGenome1). Using newly developed analytical tools, a large number of single-feature polymorphisms (SFPs) were identified. A comparison of two accessions, the reference strain Columbia (Col) and the strain Landsberg erecta (Ler), identified nearly 4000 SFPs, which...
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