Topndash;down or bottom–up regulation of intra–host blood–stage malaria: do malaria parasites most resemble the dynamics of prey or predator?

Abstract excerpt

Knowledge of the factors that limit parasite numbers offers hope of improved intervention strategies as well as exposing the selective forces that have shaped parasite life-history strategies. We develop a theoretical framework with which to consider the intra-host regulation of malaria parasite density. We analyse a general model that relates timing and magnitude of peak parasite density to initial dose under...

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