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Article

Mutation-replication statistics of polymerase chain reactions.

Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2002

Piau Didier

Abstract excerpt

The variability of the products of polymerase chain reactions, due to mutations and to incomplete replications, can have important clinical consequences. Sun (1995) and Weiss and von Haeseler (1995) modeled these errors by a branching process and introduced estimators of the mutation rate and of the efficiency of the reaction based, for example, on the empirical distribution of the mutations of a random sequence....

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PMID: 12614550
DOI: 10.1089/10665270260518308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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