Article
Chemotactic Role of Neurotropin 3 in the Embryonic Testis That Facilitates Male Sex Determination1
1 Jun 2003
Abstract excerpt
The first morphological event after initiation of male sex determination is seminiferous cord formation in the embryonic testis. Cord formation requires migration of pre-peritubular myoid cells from the adjacent mesonephros. The embryonic Sertoli cells are the first testicular cells to differentiate and have been shown to express neurotropin-3 (NT3), which can act on high-affinity trkC receptors expressed on...
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