Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caspase-Independent Exposure of Aminophospholipids and Tyrosine Phosphorylation in Bicarbonate Responsive Human Sperm Cells1

1 Jun 2003

Abstract excerpt

Only capacitated sperm cells are able to fertilize egg cells, and this process is triggered by high levels of bicarbonate. Bicarbonate renders the plasma membrane more fluid, which is caused by protein kinase A (PKA)-mediated alterations in the phospholipid (PL) bilayer. We studied exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE) in human sperm cells. Surface exposure of PS and PE on sperm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12606386
DOI: 10.1095/biolreprod.102.012500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caspase-Independent Exposure of Aminophospholipids and Tyrosine Phosphorylation in Bicarbonate Responsive Human Sperm Cells1PMID 12606386Read ↗

Functional human sperm capacitation requires both bicarbonate-dependent PKA activation and down-regulation of Ser/Thr phosphatases by Src family kinasesSemantic proximity Read ↗

Essential Role of CFTR in PKA‐Dependent Phosphorylation, Alkalinization, and Hyperpolarization During Human Sperm CapacitationSemantic proximity Read ↗

Tyrosine phosphorylation signaling regulates Ca2+ entry by affecting intracellular pH during human sperm capacitationSemantic proximity Read ↗

Capacitation-associated alkalization in human sperm is differentially controlled at the subcellular levelSemantic proximity Read ↗

A novel aminophospholipid transporter exclusively expressed in spermatozoa is required for membrane lipid asymmetry and normal fertilizationSemantic proximity Read ↗

Dissociation between AKAP3 and PKARII Promotes AKAP3 Degradation in Sperm CapacitationSemantic proximity Read ↗

Kinetics of the Progesterone-Induced Acrosome Reaction and Its Relation to Intracellular Calcium Responses in Individual Human Spermatozoa1Semantic proximity Read ↗

Human spermatozoa possess a calcium‐dependent chloride channel that may participate in the acrosomal reactionSemantic proximity Read ↗

Conserved Mechanism of Bicarbonate-Induced Sensitization of CatSper Channels in Human and Mouse SpermSemantic proximity Read ↗

Discrete Dynamic Model of the Mammalian Sperm Acrosome Reaction: The Influence of Acrosomal pH and Physiological HeterogeneitySemantic proximity Read ↗

Kinases, phosphatases and proteases during sperm capacitationSemantic proximity Read ↗

Annexin V Binding and Merocyanine Staining Fail to Detect Human Sperm CapacitationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.