Article
Specific binding of an antigen-antibody complex to apoptotic human neutrophils.
The American journal of pathology - 1 Mar 2003
Hart Simon P, Jackson Caroline, Kremmel L Maximillian, McNeill Mary S, Jersmann Hubertus, Alexander Karen M, Ross James A, Dransfield Ian
Abstract excerpt
Examination of apoptotic cell surface molecules has so far failed to reveal cell type-specific membrane alterations that serve as a signal for phagocytosis. In the present study we have identified a novel murine monoclonal antibody, BOB93, which bound to the surface of apoptotic neutrophils but not to apoptotic lymphocytes. BOB93 binding to apoptotic neutrophils was dependent on the presence of the...
Topics
- Animals
- Antibodies, Monoclonal
- Antigen-Antibody Complex
- Antigens, CD
- Apoptosis
- Binding Sites, Antibody
- Cattle
- Cell Membrane
- Genotype
- Humans
- Kinetics
- Lymphocytes
- Mice
- Neutrophils
- Receptors, IgG
