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Article

Studies on the molecular pathogenesis of extraskeletal myxoid chondrosarcoma-cytogenetic, molecular genetic, and cDNA microarray analyses.

The American journal of pathology - 1 Mar 2003

Sjögren Helene, Meis-Kindblom Jeanne M, Orndal Charlotte, Bergh Peter, Ptaszynski Konrad, Aman Pierre, Kindblom Lars-Gunnar, Stenman Göran

Abstract excerpt

Extraskeletal myxoid chondrosarcomas (EMCs) are characterized by recurrent chromosome translocations resulting in fusions of the nuclear receptor TEC to various NH(2)-terminal partners. Here we describe the phenotypic, cytogenetic, and molecular genetic characteristics of a series of 10 EMCs. Using spectral karyotyping and fluorescence in situ hybridization, clonal chromosome abnormalities were detected in all...

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Share to Artificial Gene Fusion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12598313
DOI: 10.1016/S0002-9440(10)63875-8
PMCID: PMC1868116

Genes

TEC
TCF12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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