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Article

Mutations in the B1 domain of protein G that delay the onset of amyloid fibril formation in vitro.

Protein science : a publication of the Protein Society - 1 Mar 2003

Ramírez-Alvarado Marina, Cocco Melanie J, Regan Lynne

Abstract excerpt

We previously reported that under certain experimental conditions, many variants of the B1 domain of IgG-binding protein G from Streptococcus form fibrils reproducibly. The variant I6T53 was the focus of the present study because the lag phase in the kinetics of fibril formation by this variant is significantly longer than that of other variants. This lag phase is distinguished by changes in both intrinsic...

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Identifiers

PMID: 12592027
DOI: 10.1110/ps.0227403
PMCID: PMC2312443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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