Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of the Cystathionine β Synthase (CBS) Gene During Mouse Development and Immunolocalization in Adult Brain

1 Mar 2003

Abstract excerpt

Hyperhomocysteinemia, caused by a lack of cystathionine beta synthase (CBS), leads to elevated plasma concentrations of homocysteine. This is a common risk factor for atherosclerosis, stroke, and possibly neurodegenerative diseases. However, the mechanisms that link hyperhomocysteinemia due to CBS deficiency to these diseases are still unknown. Early biochemical studies describe developmental and adult patterns...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Folate and B Vitamins Research
Share to Sulfur Compounds in Biology
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12588964
DOI: 10.1177/002215540305100311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of the Cystathionine β Synthase (CBS) Gene During Mouse Development and Immunolocalization in Adult BrainPMID 12588964Read ↗

Brain phenotype of transgenic mice overexpressing cystathionine β-synthase.Semantic proximity Read ↗

Cystathionine beta synthase deficiency affects mouse endochondral ossification.Semantic proximity Read ↗

Cystathionine β-synthase deficiency: Of mice and men.Semantic proximity Read ↗

Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse.Semantic proximity Read ↗

Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model.Semantic proximity Read ↗

Analysis of differential neonatal lethality in cystathionine β-synthase deficient mouse models using metabolic profiling.Semantic proximity Read ↗

Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia.Semantic proximity Read ↗

Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemiaSemantic proximity Read ↗

Clusterin expression during fetal and postnatal CNS development in mouseSemantic proximity Read ↗

The c.797 G>A (p.R266K) cystathionine β-synthase mutation causes homocystinuria by affecting protein stability.Semantic proximity Read ↗

The effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.Semantic proximity Read ↗

Developmental expression of monoamine oxidases A and B in the central and peripheral nervous systems of the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.