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Development and validation of a multiplexed Y-chromosome STR genotyping system, Y-PLEX 6, for forensic casework.

Journal of forensic sciences - 1 Jan 2003

Sinha Sudhir K, Budowle Bruce, Arcot Santosh S, Richey Stephen L, Chakrabor Ranajit, Jones Mary D, Wojtkiewicz Patrick W, Schoenbauer Dolores A, Gross Ann Marie, Sinha Siddhartha K, Shewale Jaiprakash G

Abstract excerpt

A Y-chromosome multiplex polymerase chain reaction (PCR) amplification kit, known as Y-PLEX 6, has been developed for use in human identification. The Y-PLEX 6 kit enables simultaneous amplification of six polymorphic short tandem repeat (STR) loci located on the non-recombinant region of the human Y-chromosome. These loci are: DYS393, DYS19, DYS38911, DYS390, DYS391, and DYS385. Our studies show that as little...

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PMID: 12570206

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