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Article

Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins.

Human molecular genetics - 1 Feb 2003

Caldwell Guy A, Cao Songsong, Sexton Elaina G, Gelwix Christopher C, Bevel John Paul, Caldwell Kim A

Abstract excerpt

Torsion dystonia is an autosomal dominant movement disorder characterized by involuntary, repetitive muscle contractions and twisted postures. The most severe early-onset form of dystonia has been linked to mutations in the human DYT1 (TOR1A) gene encoding a protein termed torsinA. While causative genetic alterations have been identified, the function of torsin proteins and the molecular mechanism underlying...

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PMID: 12554684
DOI: 10.1093/hmg/ddg027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins.PMID 12554684Read ↗

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