Article
Greater replication and differentiation of preadipocytes in inherited corticosteroid-binding globulin deficiency.
American journal of physiology. Endocrinology and metabolism - 1 May 2003
Joyner J M, Hutley L J, Bachmann A W, Torpy D J, Prins J B
Abstract excerpt
Glucocorticoids are pivotal for adipose tissue development. Rodent studies suggest that corticosteroid-binding globulin (CBG) modulates glucocorticoid action in adipose tissue. In humans, both genetic CBG deficiency and suppressed CBG concentrations in hyperinsulinemic states are associated with...
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