Article
Altered splicing pattern of TACC1 mRNA in gastric cancer.
Cancer genetics and cytogenetics - 1 Nov 2002
Line Aija, Slucka Zane, Stengrevics Aivars, Li Geng, Rees Robert C
Abstract excerpt
Transforming acidic coiled-coil (TACC) proteins are centrosome and microtubule-associated proteins that are essential for mitotic spindle function. We identified TACC1 as an immunogenic protein and a potential tumor antigen by applying serological identification of antigens by recombinant expression cloning (SEREX) technique to screen a gastric cancer cDNA library. The 5'RLM-RACE and reverse transcriptase...
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