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Article

Altered splicing pattern of TACC1 mRNA in gastric cancer.

Cancer genetics and cytogenetics - 1 Nov 2002

Line Aija, Slucka Zane, Stengrevics Aivars, Li Geng, Rees Robert C

Abstract excerpt

Transforming acidic coiled-coil (TACC) proteins are centrosome and microtubule-associated proteins that are essential for mitotic spindle function. We identified TACC1 as an immunogenic protein and a potential tumor antigen by applying serological identification of antigens by recombinant expression cloning (SEREX) technique to screen a gastric cancer cDNA library. The 5'RLM-RACE and reverse transcriptase...

Topics

Alternative Splicing
Base Sequence
DNA Primers
Fetal Proteins
Genetic Variation
Humans
Microtubule-Associated Proteins
Nuclear Proteins
Polymerase Chain Reaction
RNA, Messenger
Stomach Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

Source

Identifiers

PMID: 12547166
DOI: 10.1016/s0165-4608(02)00607-6

Genes

TACC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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