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Article

Microsomal cytochrome P450 2C5: comparison to microbial P450s and unique features.

Journal of inorganic biochemistry - 31 Aug 2000

Williams P A, Cosme J, Sridhar V, Johnson E F, McRee D E

Abstract excerpt

Although microsomal P450s represent the majority of P450s, only microbial P450s have been amenable to crystal structure solution. We have recently solved the first crystal structure of a microsomal P450, 2C5, a progesterone hydroxylase from rabbit. We discuss the features of the protein in common with existing structures of microbial P450s and limitations of homology modeling mammalian P450s based on the...

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Identifiers

PMID: 11051563
DOI: 10.1016/s0162-0134(00)00102-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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